吴风收,博士,特聘教授
地址:湖北省武汉市东湖新技术开发区光谷一路206号
金沙检测线路js95
邮编:430073
Email:wfs42@126.com; fswu@wit.edu.cn
电话:+86-27-87194980
教育背景
2009.09 - 2014.06 武汉大学化学与分子科学学院,博士
2013.01 - 2014.01 美国佐治亚理工学院 (Georgia Institute ofTechnology),联合培养博士
2010.12 - 2012.12 香港浸会大学 (Hong Kong BaptistUniversity),联合培养研究生
2005.09 - 2009.06 金沙检测线路js95,学士
工作履历
2014.07 - 至今 金沙检测线路js95,特聘教授
2015.07 - 2016.08 香港浸会大学化学系,博士后
研究领域
有机合成/药物合成:抗肿瘤药物的合成及生物活性研究;
纳米医药:有机/无机纳米制剂的制备及肿瘤诊断和治疗研究;
有机催化/仿生催化:多孔有机框架的合成及催化性质研究
招生方向:药物化学、制药化学,制药工程、药理学、药剂学、生物与医药
学术兼职
International Journal of Molecular Sciences客座编辑
全国生物基及仿生材料专家委员会委员
中国工程教育认证现场考查专家组秘书
中国化学会会员、武汉药学会会员
Chemical Science, ACS Applied Materials & Interfaces, MaterialsToday Nano, ACS Applied Nano Materials, ACS Applied Bio Materials, ACSBiomaterials Science and Engineering, Dyes and Pigments, BioconjugateChemistry, Colloids and Surfaces B, Chemical Engineering Journal等期刊的审稿人
学术成果
代表性论文(一作或通讯):
1. Y. Cao, D. Wei, L. Yang,Z. Luo, P. Yu, H. Li, C. Zhang, X. Liu, F. Wu*, M. Wu*, Y. Zeng*.Nanoplatform self-assembly from small molecules of porphyrin derivatives forNIR-II fluorescence imaging guided photothermal-immunotherapy. AdvancedHealthcare Materials, 2022, doi.org/10.1002/adhm.202102526.
2. C. Li, Z. Luo, L. Yang,J. Chen*, K. Cheng, Y. Xue, G. Liu, X. Luo, F. Wu*.Self-assembled porphyrin polymer nanoparticles with NIR-II emission and highlyefficient photothermal performance in cancer therapy. Materials Today Bio,2022, 13, 100198.
3. L. Yue, H. Li, Q. Sun, X.Luo, F. Wu*, X. Zhu*. Organic Nanoparticles based on D-A-D SmallMolecule: Self-assembly, Photophysical Properties, and SynergisticPhotodynamic/Photothermal Effects. Materials, 2022, 15,502.
4. C. Li, J. Zeng, D. Guo,L. Liu, L. Xiong*, X. Luo, Z. Hu, F. Wu*. Cobalt-doped Carbon QuantumDots with Peroxidase-Mimetic Activity for Ascorbic Acid Detection through BothFluorometric and Colorimetric Methods. ACS Applied Materials &Interfaces, 2021, 13, 49453-49461.
5. H. Li, L. Yue, L. Li*, G.Liu, J. Zhang*, X. Luo, F. Wu*. Triphenylamine-perylene diimideconjugate-based organic nanoparticles for photoacoustic imaging and cancerphototherapy. Colloids andSurfaces B: Biointerfaces, 2021,205, 111841.
6. D. Guo, C. Li, G. Liu, X.Luo, F. Wu*. Oxidase mimetic activity of metalloporphyrin-containingporous organic polymer and its applications for colorimetric detection of bothascorbic acid and glutathione. ACS Sustainable Chemistry & Engineering, 2021, 9,5412-5421.
7. D. Guo, J. Zhang*, G.Liu, X. Luo, F. Wu*. Cobalt phthalocyanine-based nanodots asefficient catalysts for chemical conversion of CO2 under ambientconditions. Journal ofMaterials Science, 2021,56, 10990-10999.
8. J. Deng, M. Yang, C. Li,G. Liu, Q. Sun*, X. Luo, F. Wu*. Single molecular-basednanoparticles with aggregation-induced emission characteristics forfluorescence imaging and efficient cancer phototherapy. Dyes and Pigments, 2021, 187,109130.
9. M. Yang, J. Deng, H. Su*,S. Gu, J. Zhang*, A. Zhong, F. Wu*. Small organic molecule-basednanoparticles with red/near-infrared aggregation-induced emission forbioimaging and PDT/PTT synergistic therapy. Materials Chemistry Frontiers, 2021, 5,406-417.
10. D. Guo, C. Li, J.Zhang*, G. Liu, X. Luo, F. Wu*. Metalloporphyrin-based porousorganic polymer as an efficient catalyst for cycloaddition of epoxides and CO2. Journal of Solid State Chemistry, 2021, 293,121770.
11. J. Zhang*, C. Yu, Z.Chen, X. Luo, H. Zhao, F. Wu*. Zeolitic imidazolateframework-8/fluorinated graphene coated SiO2 composites for pipettetip solid-phase extraction of chlorophenols in environmental and food samples. Talanta, 2021, 228,122229.
12. H. Li, L. Yue, M. Wu*, F.Wu*. Self-assembly of methylene violet-conjugated perylene diimide withphotodynamic/photothermal properties for DNA photocleavage and cancertreatment. Colloids andSurfaces B: Biointerfaces, 2020, 196, 111351.
13. L. Yue, H. Li, Q. Sun,J. Zhang, X. Luo,F. Wu*, X. Zhu*. Red-EmissiveRuthenium-Containing Carbon Dots for Bioimaging and Photodynamic CancerTherapy. ACS Applied NanoMaterials, 2020, 3, 869-876.
14. Z. Wang, L. Chen, K.Wang*, H. F. Chau, K. L. Wong*, Y. H. Fung,F. Wu*.Triphenylamine-Substituted Zinc Porphyrin Nanoparticles withPhotodynamic/Photothermal Activity for Cancer Phototherapy in Vitro. Journalof Porphyrins and Phthalocyanines, 2020, 24, 1113-1120.
15. L. Yang, J. Zhou, Z.Wang, H. Li, K. Wang*, H. Liu, F. Wu*. Biocompatible conjugatedporphyrin nanoparticles with photodynamic/photothermal performances in cancertherapy. Dyes and Pigments, 2020, 182,108664.
16. J. Deng, H. Li, M. Yang,F. Wu*. Palladium Porphyrin Complexes for Photodynamic CancerTherapy: Effect of Porphyrin Units and Metal. Photochemical & Photobiological Sciences, 2020, 19,905-912.
17. L. Chen, D. Liu, M. Wu,H. F. Chau, K. Wang*, Y. H. Fung, K. L. Wong*, Z. Wang,F. Wu*.Photodynamic and Photothermal Synergistic Behaviors of Triphenylamine-porphyrinnanoparticles for DNA Interaction, Cellular Cytotoxicity and Localization. Nanotechnology, 2020, 31,315101.
18. F. Wu,* J. Chen, L. Yue, H. Li, H. Wang*, X. Zhu*. A SimpleStrategy to Fabricate Phthalocyanine-Encapsulated Nanodots for MagneticResonance Imaging and Antitumor Phototherapy. ACS Applied Bio Materials, 2020, 3,3681-3689.
19. Z. Liu, X. Zhou, F.Wu*, Z. Liu*. Microwave-Assisted Preparation of Activated CarbonModified by Zinc Chloride as a Packing Material for Column Separation ofSaccharides. ACS Omega, 2020, 5, 10106-10114.
20. M. Yang, S. Cao, X. Sun,H. Su*, H. Li, G. Liu, X. Luo,F. Wu*. Self-AssembledNaphthalimide Conjugated Porphyrins Nanomaterials with D-A Structure forPDT/PTT Synergistic Therapy. BioconjugateChemistry,2020, 31, 663-672.
21. F. Wu,* J. Chen, H. Li, C. Li, H. Wang*, G. Liu, X. Luo, X.Zhu*. Gd (III) DOTA-functionalized phthalocyanine nanodots for magneticresonance imaging and photothermal/photodynamic therapy. Advanced Materials Interfaces, 2020, 7,2000713.
22. Y. Yu, X. Zhu, L. Wang, F.Wu*, S. Liu*, C. Chang*, X. Luo*. A simple strategy to design 3-layeredAu-TiO2 dual nanoparticles immobilized cellulose membranes with enhancedphotocatalytic activity. CarbohydratePolymers, 2020, 231, 115694.
23. F. Wu,* L. Yue, K. Cheng, J. Chen*, K. L. Wong, W.K. Wong, X. Zhu*. Facile Preparation of Phthalocyanine-Based Nanodots forPhotoacoustic Imaging and Photothermal Cancer Therapy in Vivo. ACS Biomaterials Science & Engineering, 2020, 6,5230-5239.
24. J. Zhang*, Z. Chen, S.Tang, X. Luo, J. Xi, Z. He, J. Yu*,F. Wu*. Fabrication ofporphyrin-based magnetic covalent organic framework for effective extractionand enrichment of sulfonamides. Analytica Chimica Acta, 2019, 1089, 66-77.
25. L. Yang, H. Li, D. Liu,H. Su, K. Wang*, G. Liu, X. Luo, F. Wu*. Organic Small MolecularNanoparticles Based on Self-Assembly of Amphiphilic Fluoroporphyrins forPhotodynamic and Photothermal Synergistic Cancer Therapy. Colloids and Surfaces B: Biointerfaces, 2019, 182,110345.
26. M. Yang, J. Deng, D.Guo, J. Zhang*, L. Yang, F. Wu*. Folate-Conjugated PlatinumPorphyrin Complex as a New Cancer-Targeting Photosenitizer for PhotodynamicTherapy. Organic &Biomolecular Chemistry, 2019,17, 5367-5374.
27. L. Yue, H. Li, Q. Liu,D. Guo, J. Chen, Q. Sun*, Y. Xu, F. Wu*. Manganese-doped carbonquantum dots for fluorometric and magnetic resonance (dual mode) bioimaging andbiosensing. MicrochimicaActa, 2019, 186, 315.
28. M. Yang, J. Deng, D.Guo, Q. Sun*, Z. Wang, K. Wang, F. Wu*. Mitochondria-targetingPt/Mn porphyrins as efficient photosensitizers for magnetic resonance imagingand photodynamic therapy. Dyesand Pigments, 2019, 166, 189-195.
29. F. Wu*, L. Chen, L. Yue, K. Wang, K*. Cheng, J.Chen*, X. Luo, T. Zhang. Small-Molecule Porphyrin-Based Organic Nanoparticleswith Remarkable Photothermal Conversion Efficiency for in Vivo PhotoacousticImaging and Photothermal Therapy. ACS Applied Materials & Interfaces, 2019, 11,21408-21416.
30. F. Wu*, L. Yue, L. Yang, K. Wang, G. Liu, X. Luo*, X. Zhu*.Ln(III) Chelates-Functionalized Carbon Quantum Dots: Synthesis, Optical Studiesand Multimodal Bioimaging Applications. Colloids and Surfaces B: Biointerfaces, 2019, 175,272-280.
31. F. Wu*, M. Yang, J. Zhang, S. Zhu, M. Shi, K. Wang*.Metalloporphyrin-indomethacin conjugates as new photosensitizers forphotodynamic therapy. Journalof Biological Inorganic Chemistry, 2019, 24, 53-60.
32. S. Yao, L. Chen, X. Sun,F. Jia, H. Su, H. Liu*, L. Yang, Z. Wang, F. Wu*, K. Wang*.Platinated porphyrin tailed with folic acid conjugate for cell-targetedphotodynamic activity. Journal of Luminescence, 2019, 214,116552.
33. J. Zhang*, L. Wang, A.Zhong, G. Huang, F. Wu*, D. Li, M. Teng*, J. Wang, D. Han*. DeepRed PhOLED from Dimeric Salophen Platinum (II) Complexes. Dyes and Pigments, 2019, 162,590-598.
34. L. Chen, Y. Zhao, X.Sun, J. Jiang, F. Wu*, K. Wang*. Synthesis, singlet oxygengeneration and DNA photocleavage of β, β′-conjugated polycationic porphyrins. Journal of Porphyrins and Phthalocyanines, 2019, 23,655-663.
35. H. Su, Y. Liao, F. Wu*, X. Sun, H. Liu*, K.Wang, X. Zhu*.Cetuximab-Conjugated Iodine Doped Carbon Dots as a Dual Fluorescent/CTProbe for Targeted Imaging of Lung Cancer Cells, Colloids and Surfaces B:Biointerfaces, 2018, 170, 194-200.
36. J. Jiang, D. Liu, Y.Zhao, F. Wu*, K.Yang, K. Wang*. Synthesis, DNA Binding Mode, Singlet OxygenPhotogeneration and DNA Photocleavage Activity of Metal Ruthenium Compoundswith Porphyrin-Imidazo [4,5-f] Phenanthroline Conjugated Ligand, AppliedOrganometallic Chemistry, 2018, 32, e4468.
37. F. Wu*, L. Yue, H. Su, K. Wang, L. Yang, X. Zhu.Carbon Dots @ Platinum Porphyrin Composite as Theranostic Nanoagent forEfficient Photodynamic Cancer Therapy. Nanoscale Research Letters, 2018, 13,357.
38. F. Wu, J. Chen, Z. Li, H. Su, K. C. F. Leung, H. Wang*, X. Zhu*. Red/Near-Infrared EmissiveMetalloporphyrin-Based Nanodots for Magnetic Resonance Imaging GuidedPhotodynamic Therapy in Vivo, Particle and Particle Systems Characterization,2018, 35,1800208.
39. F. Wu, H. Su, Y. Cai, W. K. Wong, W. Jiang*, X. Zhu*. Porphyrin-implanted Carbon Nanodots forPhotoacoustic Imaging and in Vivo Breast Cancer Ablation,ACS Applied Bio Materials, 2018, 1, 110-117.
40. F. Wu, M. Yang, H. Zhang*, S. Zhu, X. Zhu*, K.Wang*. Facile synthesis of sulfur-doped carbon quantum dots from vitamin B1 forhighly selective detection of Fe3+ ion, Optical Materials, 2018,77, 258-263.
41. S. Yao, Y. Zheng, L.Jiang, C. Xie, F. Wu*, C. Huang*, X. Zhang, K. L. Wong*, Z.Li, K. Wang*. Methylene violet 3RAX-conjugated porphyrin for photodynamictherapy: synthesis, DNA photocleavage, and cell study, RSC Advances,2018, 8, 4472-4477.
42. Y. Zheng, S. Zhu, L.Jiang, F. Wu*, C. Huang*, Z. Li, K. L. Wong*, Z. Xu, K. Wang*.Synthesis, Singlet Oxygen Generation, Photocytotoxicity and Subcellular Localizationof Azobisporphyrins as Potentially Photodynamic Therapeutic Agents in VitroCell Study, Journal of Porphyrins and Phthalocyanines, 2017, 21,122-127.
43. K. Yang, X. Zhang, F.Yang, F. Wu*, X. Zhang, K. Wang*. DNA Photocleavage andBinding Modes of Methylene Violet 3RAX and its Derivatives: Effect ofFunctional Groups, Australian Journal of Chemistry, 2017, 70,830-836.
44. S. Zhu, S. Yao, F.Wu*, L. Jiang, K. L. Wong*, J. Zhou, K. Wang*. PlatinatedPorphyrin as a New Organelle and Nucleus Dual-targeted Photosensitizer forPhotodynamic Therapy, Organic & Biomolecular Chemistry, 2017,15, 5764 - 5771.
45. F. Wu*,H.Su, K. Wang, W. K. Wong, X. Zhu*. Facile synthesis of N-rich carbon quantumdots from porphyrins as efficient probes for bioimaging and biosensing inliving cells, International Journal of Nanomedicine, 2017, 12,7375-7391.
46. J. Zhang*, X. Zhu, A.Zhong, F. Wu*, D. Li, H. Tong, C. Wu, W. Tang, P. Zhang, L.Wang, D. Han*. New platinum(II) one-armed Schiff base complexes for blue andorange PHOLEDs applications, Organic Electronics, 2017, 42,153-162.
47. J. Zhang*, G. Dai, F. Wu*, D. Gao, H. Jin, S. Chen, C.Huang, D. Han*. Efficient and tunable phosphorescence of newplatinum(II) complexes based on the donor–p–acceptor Schiff bases, Journalof Photochemistry and Photobiology A: Chemistry, 2016, 316,12-18.
48. F. Wu, H. Tong, K. Wang*, Z. Li*,W. Y. Wong, W. K. Wong, X. Zhu*. Synthesis, structural characterization and photophysical studies of luminescentCu(I) heteroleptic complexes based on dipyridylamine, Journal of Photochemistry and PhotobiologyA: Chemistry, 2016, 318,97-103.
49. F. Wu, H. Tong, K. Wang*, J.Zhang*, X. Zhu*. Synthesis, Crystal Structure andPhotophysical Study of Luminescent Three-Coordinate Cuprous Bromide Complexes Basedon Pyrazole Derivatives, Journal of Coordination Chemistry, 2016,69,926-933.
50. F. Wu*, H. Tong, K. Wang*, J.Zhang*, W. Y. Wong, W. K. Wong, X. Zhu*. Mononuclear Copper (I) Bromide Complexes Chelated withBis(pyrazol-1-ylmethyl)- pyridine Ligands: Structures, Electronic Propertiesand Solid State Photoluminescence, Journal of Luminescence, 2016,177, 82-87.
51. F. Wu, H. Su, X. Zhu*, K.Wang, Z. Zhang*, W. K. Wong*. Near-InfraredEmissive Lanthanide Hybridized Carbon Quantum Dots for BioimagingApplications,”Journal of Materials Chemistry B, 2016, 4, 6366-6372.
52. F. Wu, J. Li, H. Tong,Z. Li*, C. Adachi,A. Langlois, P. D. Harvey,W. Y. Wong*, W. K. Wong*, X. Zhu*.Phosphorescent Cu(I) complexes based on bis(pyrazol-1-yl-methyl)-pyridine derivatives fororganic light-emittingdiodes, Journal of Materials Chemistry C, 2015, 3,138-146.
53. F. Wu*, K. Wang, Z. Li, X. Zhu*. Design and Synthesis of Binuclear Co-Salen Catalysts for theHydrolytic Kinetic Resolution of Epoxides, Catalysis Communications, 2015,68, 101-104.
54. F. Wu, H. Tong, K. Wang*, J.Zhang*, Z. Xu, X. Zhu*.Luminescent Monomeric and Polymeric Copper(I) Halides Complexes with1,2-Bis(3,5-dimethylpyrazol-1-ylmethyl)-Benzene as Ligand, InorganicChemistry Communications, 2015, 58, 113-116.
55. F. Wu, H. Tong, Z. Li*, L. Wang, W. Y. Wong, W. K. Wong, X. Zhu*. White phosphorescent coordination polymerwith Cu2I2 alternating units linked by benzo-18-crown-6, DaltonTransactions, 2014, 43, 12463-12466.
56. F. Wu, Y. Feng,C. W. Jones*. Recyclable silica-supported iridium bipyridinecatalyst for aromatic C-H borylation, ACS Catalysis,2014,4, 1365-1375.
代表性专利:
1. Conjugated porphyrin carbonquantum dots for targeted photodynamic therapy. 2019.08.06, US10, 369, 221 B2.
2. 一种4-巯基-1-丁醇的合成工艺. ZL 2015 1 0180522. 9.
3. 具有高光热转换效率的水溶性酞菁纳米材料的制备方法及应用. ZL 2018 1 0768546. X.
4. 一种金属钌纳米材料的制备方法及抗肿瘤药物. ZL 2018 1 1610113. 8.
5. 一种金属掺杂的荧光碳量子点的制备方法. ZL 2018 1 1611248. 6.
6.一种红光碳量子点及其制备方法. 202111231037.1
7. 一种2,5-二氯苯酚的合成工艺. CN104628537A.
科研项目
1. 国家自然科学基金青年基金项目,负责人。
2. 湖北省教育厅青年人才项目,负责人。
3. 湖北省自然科学基金面上项目,负责人。
4. 湖北省青年科技晨光计划项目,负责人。
5. 湖北省教育厅重点项目,负责人。
6. 武汉市青年科技朝阳计划项目,负责人。
7. 武汉黄鹤英才项目,负责人。
奖励与荣誉
第五届“国药工程杯”全国大学生制药工程设计竞赛一等奖,2015年,指导老师
研究生杨梦倩获国家奖学金,2018年,指导老师
第九届“国药工程杯”全国大学生制药工程设计竞赛三等奖,2019年,指导老师
研究生杨梦倩获国家奖学金,2019年,指导老师
入选“武汉黄鹤英才”,2019年
研究生杨梦倩获“优秀毕业研究生”称号,2020年,指导老师
研究生邓靖燃获国家奖学金,2020年,指导老师
研究生乐亮亮、杨丽霞、杨梦倩学位论文获评校优秀硕士学位论文,2020年,指导老师
研究生邓靖燃获“优秀毕业研究生”称号,2021年,指导老师
研究生李浩兰获国家奖学金,2021年,指导老师
研究生邓靖燃、郭鼎学位论文获评校优秀硕士学位论文,2021年,指导老师
2020-2021年度我校百佳导师,2021年