陈杜刚，博士，副教授/硕士生导师
地址：湖北省武汉市东湖新技术开发区光谷一路206号，金沙检测线路js95
邮编：430205
Email：dg.chen@163.com
电话：-
教育背景
2007年−2012年 武汉大学，化学与分子科学学院，博士
2003年−2007年 武汉大学，化学与分子科学学院，学士
工作履历
2018年至今 我校，金沙检测线路js95，副教授
2019年−2020年 Georgia Institute of Technology，访问学者
2016年−2018年 我校，金沙检测线路js95，讲师
研究领域
有机光电材料的开发及其在生物医学领域、环境领域的应用：聚集诱导发光材料；抗肿瘤光敏剂；分子诊断试剂；细胞/活体荧光成像；信息防伪；环境污染物的即时检测。
招收化学工艺、药物化学、制药化学、材料与化工、生物与医药等方向的研究生。
学术成果
SCI论文：
(1) Feng,Y.; Nie, G.; Liang, W.; Li, W.; Zhang, Y.; Wang, K.; Chen, D. Real-timeimaging of acute alcoholic liver injury in vivo via a robust viscosity probewith aggregation-induced emission nature. Sens. Actuators B 2022,355, 131285.
(2) Chen,D.; Long, Z.; Zhong, C.; Chen, L.; Dang, Y.; Hu, J.-J.; Lou, X.; Xia, F.Highly Efficient Near-Infrared Photosensitizers with Aggregation-InducedEmission Characteristics: Rational Molecular Design and Photodynamic CancerCell Ablation. ACS Appl. Bio Mater. 2021,4 (6), 5231.
(3) Dang,Y.; Feng, Y.; Chen, D. Red/near-infrared biothiol fluorescent probes. Prog.Chem. 2021,33 (5), 868.
(4) Chen,D.; Nie, G.; Dang, Y.; Liang, W.; Li, W.; Zhong, C. Rational design ofnear-infrared fluorophores with a phenolic D–A type structure and constructionof a fluorescent probe for cysteine imaging. New J. Chem. 2021,45,18528.
(5) Chen,L.; Li, J.; Chen, D. Recent Advances in Fluorescent Probes forBiothiols. Chin. J. Org. Chem. 2021,41 (2), 611.
(6) Li,Y.; Chen, L.; Zhu, Y.; Chen, L.; Yu, X.; Li, J.; Chen, D. Structuremodulation on fluorescent probes for biothiols and the reversible imaging ofglutathione in living cells. RSC Adv. 2021,11 (34),21116.
(7) Nie,G.; Zhang, Y.; Zhou, Z.; Xu, J.; Wang, H.; Chen, D.; Wang, K. Dynamicevaluation of the protective effect of Dendrobium officinale polysaccharide onacute alcoholic liver injury mice in vitro and in vivo by NIR fluorescenceimaging. Anal. Bioanal. Chem. 2021,413 (23), 5715.
(8) Xiang,Y.; Yu, X.; Li, Y.; Chen, J.; Wu, J.; Wang, L.; Chen, D.; Li, J.; Zhang,Q. Covalent organic framework as an efficient fluorescence-enhanced probe todetect aluminum ion. Dyes Pigm. 2021,195, 109710.
(9) Chen,L.; Feng, Y.; Dang, Y.; Zhong, C.; Chen, D. A deep-red emissionfluorescent probe with long wavelength absorption for viscosity detection andlive cell imaging. Anal. Bioanal. Chem. 2020,412 (28),7819.
(10) Chen,D.; Feng, Y. Recent Progress of Glutathione (GSH) Specific FluorescentProbes: Molecular Design, Photophysical Property, Recognition Mechanism andBioimaging. Crit. Rev. Anal. Chem. 2020,DOI:10.1080/10408347.2020.1819193.
(11) Dang,Y.; Chen, L.; Yuan, L.; Li, J.; Chen, D. A New Fluorescent Probe forSelective Detection of Endogenous Cysteine and Live Cell Imaging. ChemistrySelect2020,5 (2), 584.
(12) Long,Z.; Chen, L.; Dang, Y.; Chen, D.; Lou, X.; Xia, F. An ultralowconcentration of two-photon fluorescent probe for rapid and selective detectionof lysosomal cysteine in living cells. Talanta 2019,204,762.
(13) Chen,D.; Long, Z.; Sun, Y.; Luo, Z.; Lou, X. A red-emission probe forintracellular biothiols imaging with a large Stokes shift. J. Photochem.Photobiol. A: Chem. 2019,368, 90.
(14) Chen,D.; Long, Z.; Dang, Y.; Chen, L. A new fluorescent probe for specificdetection of cysteine with facile preparation and living cell imaging. DyesPigm. 2019,166, 266.
(15) Chen,D.; Long, Z.; Dang, Y.; Chen, L. A novel fluorescent probe with redemission and a large Stokes shift for selective imaging of endogenous cysteinein living cells. Analyst 2018,143 (23), 5779.
(16) Chen,D.; Yang, J.; Dai, J.; Lou, X.; Zhong, C.; Yu, X.; Xia, F. A low backgroundD–A–D type fluorescent probe for imaging of biothiols in living cells. J.Mater. Chem. B 2018,6 (32), 5248.
(17) Sun,Y.; Luo, S.; Sun, H.; Zeng, W.; Ling, C.; Chen, D.; Chan, V.; Liao, K.Engineering closed-cell structure in lightweight and flexible carbon foamcomposite for high-efficient electromagnetic interference shielding. Carbon 2018,136, 299.
(18) Sun,Y.; Zeng, W.; Sun, H.; Luo, S.; Chen, D.; Chan, V.; Liao, K. Inorganic/polymer-graphenehybrid gel as versatile electrochemical platform for electrochemical capacitorand biosensor. Carbon 2018,132, 589.
(19) Chen,D.; Zhong, C.; Zhao, Y.; Nan, L.; Liu, Y.; Qin, J. A two-dimensionalmolecule with a large conjugation degree: synthesis, two-photon absorption andcharge transport ability. J. Mater. Chem. C 2017,5 (21),5199.
(20) Chen,D.; Zhong, C.; Zhao, Y.; Liu, Y.; Qin, J. Synthesis and properties of aseries of quinoxaline-based copolymers: an example to understand the effect ofthe structure of the mainchain and sidechain on the charge transport ability ofthe polymers. Mater. Chem. Front. 2017,1 (10), 2085.
(21) Yu,X.; Wan, J.; Chen, S.; Li, M.; Gao, J.; Yang, L.; Wang, H.; Chen, D.;Pan, Z.; Li, J. Pyridine-ring containing twisttetraazaacene: Synthesis,physical properties, crystal structure and picric acid sensing. Talanta 2017,174, 462.
(22) Chen,D.; Chen, P.; Zong, L.; Sun, Y.; Liu, G.; Yu, X.; Qin, J. Colorimetric andfluorescent probes for real-time naked eye sensing of copper ion in solutionand on paper substrate. R. Soc. Open Sci. 2017,4 (11),171161.
授权发明专利：
1.陈杜刚，罗子娟，陈莉，党耶城，一种发射近红外光的荧光染料及其制备方法，授权公告号：CN 110194900 B
2.陈杜刚，余响林，黎俊波，屈宏庆，一种溶酶体靶向荧光探针及其制备方法，授权公告号：CN 107226783 B
3.陈杜刚，余响林，黎俊波，刘佳俊，王哲，一种双通道铜离子检测试纸及其制备方法，授权公告号：CN 107831165 B
科研项目
国家自然科学基金，青年项目，主持
湖北省教育厅重点项目，主持
获奖情况
2018年：湖北省第十一届大学生化学（化工）学术创新成果报告会二等奖（指导教师）
2020年：“互联网+”大学生创新创业大赛，高教主赛道中校创意组银奖（指导教师）
2021年：一位硕士生获“优秀毕业研究生”称号，两位毕业生荣获“优秀硕士学位论文”
